for treatment-resistant depression...

The end of the road

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Cape Town, Western Cape

Bedfordview, Gauteng

Hilton, KZN

Umhlanga, KZN

Now open!

the treatment of resistant depression, suicidality and chronic pain

Ketamine Infusion Therapy is a novel paradigm in

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South Africa registered with the American Society of Ketamine Physicians (ASKP).

Ketamine Infusion provider in

The KCSA founder is the only

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accredited members of SOKePSA.

KCSA medical and nursing staff are all

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restoring purpose

offering hope, rebuilding lives,

Ketamine Infusion Therapy

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Why should I consider Ketamine?

Major Depression is a devastating and costly disease at many levels.

Those who don’t respond to traditional antidepressants often embark on a trajectory of ever-increasing doses, combinations of different drugs, behavioural therapy and repeated electroconvulsive therapy (ECT). Eventually they might be described as ‘Treatment Resistant’ and hope is all but lost.

Ketamine targets specific receptors in the brain and has been demonstrated to repair damaged synapses (junctions between nerves) in a predictable and sustained manner. Instead of simply ‘numbing the senses, Ketamine offers a transformative awakening, realignment of purpose and restoration of hope in responsive patients.

Dr Alan Howard (Founder and National Medical Director) discovered that there was a substantial and growing body of evidence supporting the use of Ketamine for mood disorders and after studying the various protocols, he decided to concentrate his attention on bringing home the new paradigm of Ketamine Infusion Therapy to those trapped in the devastating cycle of resistant depression, suicidality and chronic pain back home in his native South Africa.

‘My focus as an Emergency Physician is saving lives. Whether I save the life of a car crash victim in the resuscitation room or prevent a suicide through Ketamine Infusion Therapy it’s still a life saved and I’ve fulfilled my purpose.’ 

Dr Alan Howard (Founder and National Medical Director).


What Our Patients Say

Video Testimonials

View Ketamine video testimonials from around the world

0 Deaths by suicide, globally each year.
Every 0 Seconds there is a suicide attempt.
Every 0 Seconds someone dies from suicide.

Our Mission

We will offer new hope to those with resistant mood disorders and chronic pain in a professional, compassionate, safe and affordable manner through the novel paradigm of Ketamine Infusion Therapy.

Our Vision

We aspire to provide unparalleled care and safety standards as the most trusted name in the field of Ketamine Infusion Therapy in South Africa.

Our Pledge

We promise to treat our patients with respect, dignity and compassion. We will neither judge nor breach confidence. We will tirelessly pursue the restoration of happy, meaningful lives for all our patients through the appropriate and safe administration of Ketamine.


Have some Questions?

Ketamine was developed as an anaesthetic in the 1960’s and is one of the most widely used and safest anaesthetic agents in the world. About 12-years ago it was discovered that Ketamine infusions at much lower doses could rapidly reverse major depression and suicidality and that a series of infusions actually repaired damaged nerve fibres and synapses (nerve junctions) in the brain. Most traditional antidepressants target the receptors in the brain mediated by the neurotransmitters serotonin and nor-adrenaline and take weeks to work, if at all. Ketamine targets another, much more prevalent receptor (NMDA) causing an increase in levels of the neurotransmitter glutamate that has an almost immediate effect in most cases. 70% of patients with treatment resistant depression experience reduction in suicidal thoughts after only one infusion.

Ketamine also disrupts the feedback loop of chronic pain in the brain and can provide remission from refractory migraines, CRPS , fibromyalgia and other types of pain.

When used as an anaesthetic, the dose of ketamine is about four-times as high as that used for our treatments and is given as a bolus over only a few minutes. Because patients still retain the ability to protect their own airway, breathe normally and usually experience no significant cardiovascular effects, ketamine is considered extremely safe compared with other anaesthetic agents. The dose you will receive at KCSA is far less and given as a controlled infusion over 40-minutes for depression and 4-hours for chronic pain conditions.

Even though ketamine has an established safety profile, we still exercise every caution at KCSA and your infusion will be administered by doctors and nurses with appropriate training and with immediate access to emergency drugs and equipment.

Before your infusion a medical history will be taken and your weight will be recorded. A standard pre-anaesthetic assessment will be conducted by the doctor.

A small cannula will be placed in a vein on the back of your hand or forearm by a nurse or doctor and your infusion will always be started by a doctor. The weight-based preparation of the infusion will be checked by both a doctor and a nurse. We require our doctors to have experience using ketamine and training in anaesthesia and airway management. Our nurses are required to have experience in Intensive Care Units or Emergency Departments and are therefore familiar with the monitors used to check on you throughout the infusion. A doctor will be immediately available throughout your infusion.

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Associations, Affiliations, Memberships and Accreditations

Our founder and National Medical Director is a member of: